3zlc

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Template:STRUCTURE 3zlc

Contents

Crystal Structure of Erv41p

Template:ABSTRACT PUBMED 23524136

Function

[ERV41_YEAST] Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. The C-terminal Ile-Leu motif is required for exit from the endoplasmic reticulum. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum.[1] [2]

About this Structure

3zlc is a 2 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.

Reference

  1. ↑ Otte S, Belden WJ, Heidtman M, Liu J, Jensen ON, Barlowe C. Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex. J Cell Biol. 2001 Feb 5;152(3):503-18. PMID:11157978
  2. ↑ Otte S, Barlowe C. The Erv41p-Erv46p complex: multiple export signals are required in trans for COPII-dependent transport from the ER. EMBO J. 2002 Nov 15;21(22):6095-104. PMID:12426381

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