4c8u

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Template:STRUCTURE 4c8u

Xenopus ZNRF3 ectodomain crystal form II

Function

[ZNRF3_XENTR] E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components (By similarity).

About this Structure

4c8u is a 2 chain structure with sequence from Xenopus (silurana) tropicalis. Full crystallographic information is available from OCA.

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