4o1z

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Template:STRUCTURE 4o1z

Contents

Crystal Structure of Ovine Cyclooxygenase-1 Complex with Meloxicam

Template:ABSTRACT PUBMED 24425867

Function

[PGH1_SHEEP] May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.

About this Structure

4o1z is a 2 chain structure with sequence from Ovis aries. Full crystallographic information is available from OCA.

Reference

  • Xu S, Hermanson DJ, Banerjee S, Ghebreselasie K, Clayton GM, Garavito RM, Marnett LJ. Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network. J Biol Chem. 2014 Jan 14. PMID:24425867 doi:http://dx.doi.org/10.1074/jbc.M113.517987

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OCA

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