Tripeptidyl peptidase

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 3ee6

Tripeptidyl peptidase (TPP) is an enzyme which cleaves N-terminal tripeptides from polypeptides. TPP-I functions in lysosomes, TPP-II is part of the ubiquitin-proteasome pathway.

Contents 1 3D Structures of Tripeptidyl peptidase 1.1 TPP-I 1.2 TPP-II 1.3 TPP-IV

3D Structures of Tripeptidyl peptidase

TPP-I

3ee6 – TPP-I – human
3edy – hTPP-I precursor residues 20-563

TPP-II

3lxu – TPP-II residues 463-770 – Drosophila melanogaster

TPP-IV

2eep – PgPro-TPP-IV+inhibitor – Porphyromonas gingivalis
2d5l - PgPro-TPP-IV
2z3w - PgPro-TPP-IV (mutant)
2z3z, 2dcm - PgPro-TPP-IV (mutant)+inhibitor