4gqp

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Template:STRUCTURE 4gqp

Structure based design of sub-nanomolar affinity anti-methamphetamine single chain antibodies.

Template:ABSTRACT PUBMED 24419156

About this Structure

4gqp is a 1 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.

Reference

  • Thakkar S, Nanaware-Kharade N, Celikel R, Peterson EC, Varughese KI. Affinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering. Sci Rep. 2014 Jan 14;4:3673. doi: 10.1038/srep03673. PMID:24419156 doi:http://dx.doi.org/10.1038/srep03673

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OCA

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