User:Kurt Corsbie/Sandbox 1

From Proteopedia

Metabotropic Glutamate Receptor 5 mGlu5 Homo sapiens

Class C GPCR

spinqualitylabelsall models Caption for this structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Image:PDBimage1.png Figure Legend Contents 1 Function 2 Structure 2.1 Domain highlights 3 Disease 4 Relevance 5 Structural highlights Function Tacos are good. [1] Structure Hydrophobic Pocket Surrounding Mavoglurant Image:Mav HB 1.1.png Hydrogen Bonding interactions between protein and Mavoglurant Further Hydrogen Bonding between protein and Mavoglurant Domain highlights Disease Relevance Structural highlights (mGLu5)

References

1. ↑ Dore AS, Okrasa K, Patel JC, Serrano-Vega M, Bennett K, Cooke RM, Errey JC, Jazayeri A, Khan S, Tehan B, Weir M, Wiggin GR, Marshall FH. Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain. Nature. 2014 Jul 31;511(7511):557-62. doi: 10.1038/nature13396. Epub 2014 Jul 6. PMID:25042998 doi:http://dx.doi.org/10.1038/nature13396