Sandbox Reserved 1298

From Proteopedia

proteopedia linkproteopedia link

Contents 1 genetics is ok 2 'Molecules it Interacts With and where ' 3 'Origin' 4 'Structure' 5 'Molecules it Interacts With and where ' 6 'Origin' 7 'Structure' 8 'Function" 9 Connor McDermott and Niall Cope's Structure:E.coli RNA Polymerase sigma-70 Holoenzyme 10 Functions!!!!!!!!!!!!!!!!!!!!!!!!Lawl XD 11 What it interacts 12 Interaction (Where, When, How, Why, End My Suffering) 13 Is it from Kenya?? Where's the Birth Certificate 14 Disease 15 Relevance 16 Structural highlights 17 Fun Fax, b

genetics is ok

'Molecules it Interacts With and where '

The protein binds to GDP as well as the following ligands in order to promote the attachment of the protein complex to the ribosome A site.

PHOSHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER

PHENYLALANINE MAGNESIUM ION

'Origin'

It has domains that are created in yeast (phenyl-transfer RNA) , in the heat resistant Thermus aquaticus (EF-Tu elongation factor, and can be synthetically manufactured.

'Structure'

It has 3 domains. G proteins, Elongation Factors, and the EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain. It is composed of 6 chains, which combine in alignment.

Specific are highlighted here. The ligands listed above, GDP, Phe, and Mg+2 ion each attach at these locations which are still being explored.

which play a crucial role in binding to the ribosome during translation. They form positive pockets with which negative amino acids can bind to.

'Molecules it Interacts With and where '

The protein binds to GDP as well as the following ligands in order to promote the attachment of the protein complex to the ribosome A site.

PHOSHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER

PHENYLALANINE MAGNESIUM ION

'Origin'

It has domains that are created in yeast (phenyl-transfer RNA) , in the heat resistant Thermus aquaticus (EF-Tu elongation factor, and can be synthetically manufactured.

'Structure'

It has 3 domains. G proteins, Elongation Factors, and the EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain. It is composed of 6 chains, which combine in alignment.

Specific are highlighted here.

which play a crucial role in binding to the ribosome during translation.

'Function"

The protein complex participates in placing the amino acids in their correct order when messenger RNA is translated into a protein sequence on the ribosome by promoting GTP-dependent binding of tRNA to the A site of the ribosome. In other words, it is involved with elongation during polypeptide synthesis.

spinqualitylabelsall models Phe-tRNA, elongation factor EF-TU:GDPNP Ternary complex Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Heterodimer </scene> alignment. Specific are highlighted here. The ligands listed above, GDP, Phe, and Mg+2 ion each attach at these locations which are still being explored. which play a crucial role in binding to the ribosome during translation. They form positive pockets with which negative amino acids can bind to. 'Molecules it Interacts With and where ' The protein binds to GDP as well as the following ligands in order to promote the attachment of the protein complex to the ribosome A site. PHOSHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER PHENYLALANINE MAGNESIUM ION 'Origin' It has domains that are created in yeast (phenyl-transfer RNA) , in the heat resistant Thermus aquaticus (EF-Tu elongation factor, and can be synthetically manufactured. 'Structure' It has 3 domains. G proteins, Elongation Factors, and the EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain. It is composed of 6 chains, which combine in alignment. Specific are highlighted here. which play a crucial role in binding to the ribosome during translation.

Connor McDermott and Niall Cope's Structure:E.coli RNA Polymerase sigma-70 Holoenzyme

spinqualitylabelsall models RNA Polymerase Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Functions!!!!!!!!!!!!!!!!!!!!!!!!Lawl XD

What it interacts

Interaction (Where, When, How, Why, End My Suffering)

Is it from Kenya?? Where's the Birth Certificate

E. Coli, so I guess

Disease

E.coli use it, so I guess salmonella.

Relevance

It's lit G.

Structural highlights

Check ESPN, my guy

Fun Fax, b

Most studied bacterial RNA polymerase. The Donald's favorite bacterial RNA polymerase.

</StructureSection>