2gzl

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Image:2gzl.gif


PDB ID 2gzl

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, resolution 2.50Å
Ligands: , and
Gene: ispF, mecS (Escherichia coli)
Activity: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, with EC number 4.6.1.12
Coordinates: save as pdb, mmCIF, xml



Structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with a CDP derived fluorescent inhibitor


About this Structure

2GZL is a Single protein structure of sequence from Escherichia coli. This structure supersedes the now removed PDB entry 2AO4. Full crystallographic information is available from OCA.

Reference

Fluorescent inhibitors for IspF, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy., Crane CM, Kaiser J, Ramsden NL, Lauw S, Rohdich F, Eisenreich W, Hunter WN, Bacher A, Diederich F, Angew Chem Int Ed Engl. 2006 Feb 6;45(7):1069-74. PMID:16392111

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