2h09

Structural highlights

Function

[MNTR_ECOLI] In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Patzer SI, Hantke K. Dual repression by Fe(2+)-Fur and Mn(2+)-MntR of the mntH gene, encoding an NRAMP-like Mn(2+) transporter in Escherichia coli. J Bacteriol. 2001 Aug;183(16):4806-13. PMID:11466284 doi:http://dx.doi.org/10.1128/JB.183.16.4806-4813.2001
2. ↑ Waters LS, Sandoval M, Storz G. The Escherichia coli MntR miniregulon includes genes encoding a small protein and an efflux pump required for manganese homeostasis. J Bacteriol. 2011 Nov;193(21):5887-97. doi: 10.1128/JB.05872-11. Epub 2011 Sep 9. PMID:21908668 doi:http://dx.doi.org/10.1128/JB.05872-11