Structural highlights
Function
PA2A_GLOHA Snake venom phospholipase A2 (PLA2) that acts in vivo as an anti-thrombotic agent. Inhibits platelet aggregation induced by ADP, arachidonic acid, and thrombin. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
See Also
References
- ↑ Wang Y, Cui G, Zhao M, Yang J, Wang C, Giese RW, Peng S. Bioassay-directed purification of an acidic phospholipase A(2) from Agkistrodon halys pallas venom. Toxicon. 2008 Jun 1;51(7):1131-9. doi: 10.1016/j.toxicon.2008.01.003. Epub 2008, Jan 17. PMID:18456297 doi:http://dx.doi.org/10.1016/j.toxicon.2008.01.003
