Thioredoxin Reductase
From Proteopedia
Thioredoxin Reductase (TrxR) is an enzyme which reduces thioredoxin using NADPH. TrxR-2 is mitochondrial. The images at the left and at the right correspond to one representative TrxR, i.e. the crystal structure of Thioredoxin Reductase from Eschericia coli (1cl0). For more details see User:Sarah Abdalla/Thioredoxin Reductase.
3D Structures of Thioredoxin Reductase
Update June 2011
TrxR
1cl0, 1tde, 1trb – EcTrxR+FAD – Eschericia coli
1tdf - EcTrxR+FAD+NADPH
1f6m - EcTrxR (mutant)+Trx-1+FAD+AADPH
1h6v – rTrxR (mutant)+FAD+NADPH – rat
1vdc – TrxR+FAD – Arabidopsis thaliana
2a87 - TrxR+FAD+NADPH – Mycobacterium tuberculosis
3cty - TrxR+FAD – Thermoplasma acidophilum
3d8x - yTrxR+FAD+NADPH - yeast
2nvk - DmTrxR+FAD+NADPH – Drosophila melanogaster
2q0k, 2q0l - HpTrxR+FAD+NADPH – Helicobacter pylori
3ish - HpTrxR+FAD
2q7v - TrxR+FAD – Deinococcus radiodurans
3r9u – TrxR – Campylobacter jejuni
TrxR-1
2cfy – hTrxR-1+FAD – human
2zz0, 2zzb, 2zzc – hTrxR-1 (mutant)+FAD
2j3n – hTrxR-1+FAD+NADPH
3itj – yTrxR-1+FAD
3dh9, 3dgh – DmTrxR-1+FAD
3ean, 3eao – rTrxR-1+FAD+NADPH
TrxR-2
1zdl, 1zkq – mTrxR-2+FAD+NADPH – mouse
3dgz – mTrxR-2+FAD
2whd – TrxR-2+FAD – Hordeum vulgare
TrxR-3
3f8d, 3f8p, 3f8r – TrxR-3 (mutant)+FAD – Sulfolobus solfataricus
3h8q – hTrxR-3 glutaredoxin domain
