1ahj
From Proteopedia
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NITRILE HYDRATASE
Overview
BACKGROUND: Nitrile hydratases are unusual metalloenzymes that catalyze, the hydration of nitriles to their corresponding amides. They are used as, biocatalysts in acrylamide production, one of the few commercial scale, bioprocesses, as well as in environmental remediation for the removal of, nitriles from waste streams. Nitrile hydratases are composed of two, subunits, alpha and beta, and they contain one iron atom per alphabeta, unit. We have determined the crystal structure of photoactivated, iron-containing nitrile hydratase from Rhodococcus sp. R312 to 2.65 A, resolution as a first step in the elucidation of its catalytic mechanism., RESULTS: The alpha subunit consists of a long N-terminal arm and a, C-terminal domain that forms a novel fold. This fold can be described as a, four ... [(full description)]
About this Structure
1AHJ is a [Protein complex] structure of sequences from [Rhodococcus sp. r312] with FE as [ligand]. Active as [Nitrile hydratase], with EC number [4.2.1.84]. Structure known Active Sites: FEA, FEC, FEE and FEG. Full crystallographic information is available from [OCA].
Reference
Crystal structure of nitrile hydratase reveals a novel iron centre in a novel fold., Huang W, Jia J, Cummings J, Nelson M, Schneider G, Lindqvist Y, Structure. 1997 May 15;5(5):691-9. PMID:9195885
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