Ribonuclease inhibitor

From Proteopedia

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spinqualitylabelsall models Structure of hRI complexed with RNase I, 1z7x Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Human ribonuclease inhibitor (hRI) is a protein that binds to and inhibits ribonucleases. Ribonucleases(RNase) are a family of enzymes that degrade RNA. RNases are often cytotoxic which gives them unique cancer fighting properties. However, when bound to an RI they no longer display catalytic ability.

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Interactions between hRI and RNase 1 ^[1]