3dl5

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Template:STRUCTURE 3dl5

Contents 1 Crystal Structure of the A287F Active Site Mutant of TS-DHFR from Cryptosporidium hominis 2 About this Structure 3 See Also 4 Reference

Crystal Structure of the A287F Active Site Mutant of TS-DHFR from Cryptosporidium hominis

Template:ABSTRACT PUBMED 18672899

About this Structure

3dl5 is a 5 chain structure of Dihydrofolate reductase and Thymidylate synthase with sequence from Cryptosporidium hominis. Full crystallographic information is available from OCA.

See Also

• Dihydrofolate reductase
• Thymidylate synthase

Reference

• Martucci WE, Vargo MA, Anderson KS. Explaining an unusually fast parasitic enzyme: folate tail-binding residues dictate substrate positioning and catalysis in Cryptosporidium hominis thymidylate synthase. Biochemistry. 2008 Aug 26;47(34):8902-11. Epub 2008 Aug 2. PMID:18672899 doi:10.1021/bi800466z