2a5p

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Image:2a5p.png

Template:STRUCTURE 2a5p

Monomeric parallel-stranded DNA tetraplex with snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, NMR, 8 struct.

Template:ABSTRACT PUBMED 16408022

About this Structure

2a5p is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Phan AT, Kuryavyi V, Gaw HY, Patel DJ. Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter. Nat Chem Biol. 2005 Aug;1(3):167-73. Epub 2005 Jul 17. PMID:16408022 doi:nchembio723
  • Ma DL, Che CM, Yan SC. Platinum(II) complexes with dipyridophenazine ligands as human telomerase inhibitors and luminescent probes for G-quadruplex DNA. J Am Chem Soc. 2009 Feb 11;131(5):1835-46. PMID:18998644 doi:10.1021/ja806045x

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OCA

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