Ras GTPase activating protein

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Image:2gqi.png
NMR Structure of the Ras GTPase activating protein, 2gqi

Template:STRUCTURE 2j05
















Ras GTPase activating protein (RasGAP) inactivates Ras from its active GTP-bound form to its GDP-bound form. It is part of the mitogenic signal transmission via its N-terminal SH2-SH3-SH2 domains. The images on the left and right correspond to one representative RasGAP structure, i.e. the human RasGAP SH3 domain (2gqi).

Contents








3D Structures of Ras GTPase activating protein

2gqi – hRasGAP SH3 domain – human – NMR
2j05, 2j06 - hRasGAP SH3 domain
2gsb - hRasGAP SH2 domain – NMR
3bxj - hRasGAP SYNGAP fragment - rat

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Michal Harel, Alexander Berchansky

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