4lir

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Template:STRUCTURE 4lir

Contents

Crystal structure of a nucleoporin 35kDa (NUP35) from Homo sapiens at 2.46 A resolution

Function

[NUP53_HUMAN] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs). Can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC.[1]

About this Structure

4lir is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. ↑ Hawryluk-Gara LA, Shibuya EK, Wozniak RW. Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex. Mol Biol Cell. 2005 May;16(5):2382-94. Epub 2005 Feb 9. PMID:15703211 doi:10.1091/mbc.E04-10-0857

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