Guanylate kinase

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Revision as of 07:12, 27 November 2014 by Michal Harel (Talk | contribs)
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Template:STRUCTURE 1gky

Guanylate kinase (GK) catalyzes the transfer of phosphate from GMP to GDP using ATP as a phosphate source. GK is essential for recycling GMP and cGMP. GK also forms a domain in the membrane-associated GK (MAGUK) which functions in mitotic spindle orientation and cell adhesion. There is a single mutation in GK which converts it to a GK domain. The GK domain has no catalytic activity. The MAGUK contain PDZ, WW, SH3 and GK domains.

3D structures of guanylate kinase

Updated on 27-November-2014

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Michal Harel, Alexander Berchansky

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