Tripeptidyl peptidase

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Image:2d5l.png
Crystal Structure of Tripeptidyl peptidase (2d5l)

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Tripeptidyl peptidase (TPP) is an enzyme which cleaves N-terminal tripeptides from polypeptides.

  • TPP-I functions in lysosomes.
  • TPP-II is part of the ubiquitin-proteasome pathway.
  • TPP-IV is a serine exopeptidase which cleaves proline dipeptides from the N-terminus of polypeptides.

3D Structures of Tripeptidyl peptidase

Updated on 15-December-2014

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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