12-oxophytodienoate reductase

Function

12-oxophytodienoate reductase (OPR) catalyzes the conversion of (green) to 3-oxo-pentenyl-cyclopentane octanoate. The expression of OPR is induced by stimuli like touch, wind, wounding, UV light and detergent. OPR uses the cofactor (cyan) which is reduced by NADPH. . OPR exhibits self inhibition by dimerization. Three isozymes of OPR are known – OPR1, OPR2, OPR3.

• OPR1 cleaves olefinic bonds in α,β-unsaturated carbonyls.
  
• OPR3 cleaves olefinic bonds in cyclic enones.

Relevance

OPR is part of the jasmonic acid synthesis pathway. Jasmonic acid is regulating plant responses to abiotic and biotic stresses.