Transthyretin

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Transthyretin (TTR) is a serum carrier of the thyroid hormone thyroxine (T4) and retinol through its association with retinol-binding protein (RBP). Many small molecules bind to TTR T4-binding site. TTR is known to be associated with amyloid diseases. For details see Student Project 2 for UMass Chemistry 423 Spring 2015.

3D structures of transthyretin

Updated on 22-February-2016

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Michal Harel, Alexander Berchansky

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