Ras GTPase activating protein

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Template:STRUCTURE 2j05

Ras GTPase activating protein (RasGAP) inactivates Ras from its active GTP-bound form to its GDP-bound form^[1]. It is part of the mitogenic signal transmission via its N-terminal SH2-SH3-SH2 domains.

3D Structures of Ras GTPase activating protein

Updated on 03-August-2016

2gqi, 2m51 – hRasGAP SH3 domain – human – NMR
2j05, 2j06, 4fss - hRasGAP SH3 domain
2gsb - hRasGAP SH2 domain – NMR
3bxj - hRasGAP SYNGAP fragment - rat

References

1. ↑ Tocque B, Delumeau I, Parker F, Maurier F, Multon MC, Schweighoffer F. Ras-GTPase activating protein (GAP): a putative effector for Ras. Cell Signal. 1997 Feb;9(2):153-8. PMID:9113414