Xylosidase

From Proteopedia

spinqualitylabelsall models Structure of α-xylosidase family 31 complex with pentaerythritol propoxylate, sulfate, Ni+2 (small green) and Cl- (large green) ions (PDB entry 2xvl) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function Xylosidase (XYL) catalyzes the hydrolysis of α- or β-glycosidic linkages. β-XYL catalyzes the endo-hydrolysis of 1,4-β-D-glycosidic or endo-hydrolysis of 1,3-β-D-glycosidic linkage[1]. α-XYL catalyzes the exo-hydrolysis of 1,4-β-D-glycosidic or exo-hydrolysis of 1,3-β-D-glycosidic linkage from the non-reducing termini of xylans[2]. XYL catalyzes the conversion of cellulose and hemicellulose xylan to xylose. Structural highlights The active site of α-xylosidase contains the xyloglucan and nucleophilic water[3].

3D Structures of xylosidase

Updated on 15-December-2016

References

1. ↑ Martinez GA, Chaves AR, Civello PM. beta-xylosidase activity and expression of a beta-xylosidase gene during strawberry fruit ripening. Plant Physiol Biochem. 2004 Feb;42(2):89-96. PMID:15283123 doi:http://dx.doi.org/10.1016/j.plaphy.2003.12.001
2. ↑ Moracci M, Cobucci Ponzano B, Trincone A, Fusco S, De Rosa M, van Der Oost J, Sensen CW, Charlebois RL, Rossi M. Identification and molecular characterization of the first alpha -xylosidase from an archaeon. J Biol Chem. 2000 Jul 21;275(29):22082-9. PMID:10801892 doi:http://dx.doi.org/10.1074/jbc.M910392199
3. ↑ Larsbrink J, Izumi A, Ibatullin F, Nakhai A, Gilbert HJ, Davies GJ, Brumer H. Structural and enzymatic characterisation of a Glycoside Hydrolase Family 31 alphaxylosidase from Cellvibrio japonicus involved in xyloglucan saccharification. Biochem J. 2011 Mar 22. PMID:21426303 doi:10.1042/BJ20110299