2gzl
From Proteopedia
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| , resolution 2.50Å | |||||||
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| Ligands: | , , | ||||||
| Gene: | ispF, mecS (Escherichia coli) | ||||||
| Activity: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, with EC number 4.6.1.12 | ||||||
| Related: | 1GX1, 1KNJ, 1U3P, 2AMT
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with a CDP derived fluorescent inhibitor
About this Structure
2GZL is a Single protein structure of sequence from Escherichia coli. This structure supersedes the now removed PDB entry 2AO4. Full crystallographic information is available from OCA.
Reference
Fluorescent inhibitors for IspF, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy., Crane CM, Kaiser J, Ramsden NL, Lauw S, Rohdich F, Eisenreich W, Hunter WN, Bacher A, Diederich F, Angew Chem Int Ed Engl. 2006 Feb 6;45(7):1069-74. PMID:16392111
Page seeded by OCA on Mon Mar 31 03:23:23 2008
