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General Description
Human polymerase θ (pol θ) is large, 290kD enzyme consisting of three distinct domains (1,2). An N-terminal helicase-like domain, whose exact cellular functions are a topic of on-going debate and research, is linked to a C-terminal polymerase domain by a large and disordered central region (2).
Structural Highlights
Structural Insights into Function
Related Proteins
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