Dihydroorotase (DHO) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate[1].
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Structural highlights
The 3D structure of the complex of DHO with dihydroorotate shows the substrate bound to the protein via electrostatic interactions.
References
↑ Porter TN, Li Y, Raushel FM. Mechanism of the dihydroorotase reaction. Biochemistry. 2004 Dec 28;43(51):16285-92. doi: 10.1021/bi048308g. PMID:15610022 doi:http://dx.doi.org/10.1021/bi048308g
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