User:Eric Martz/Sandbox 3

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Contents 1 ConSurf Prototype 1.1 Scenes 1.2 User Interface & Color Key 1.3 Scripts

ConSurf Prototype

spinqualitylabelsall models PDB ID 2hhd Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
2hhd, resolution 2.20Å ()
Ligands:	,
Structural annotation: Resources: CATH : 2Hhda00, 2Hhdb00, 2Hhdc00, 2Hhdd00 InterPro : Ipr002339, Ipr002338, Ipr000971, Ipr009050, Ipr002337, Ipr012292 Pfam : PF00042 SCOP : d2hhda_, d2hhdb_, d2hhdc_, d2hhdd_ UniProt : P69905, P68871
Functional annotation: Cellular component: hemoglobin complex Biological process: transport oxygen transport positive regulation of nitric oxide biosynthetic process nitric oxide transport regulation of blood vessel size regulation of blood pressure Molecular function: oxygen binding protein binding metal ion binding oxygen transporter activity heme binding iron ion binding hemoglobin binding selenium binding
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Scenes

Opening the proposed Evolutionary Conservation section below the molecule would automatically color all chains by ConSurf, and spacefill them. Checkboxes in this section, one per chain, would be checked when the section is first opened. Unchecking a given chain would render it as a gray backbone (as in ConSurf). Ligands will be ball and stick, with dot surfaces, colored by element (as in ConSurf).

• (2 alphas, A and C, and 2 betas, B and D, in 2HHD).
• (one alpha, one beta)
• (both alphas)

User Interface & Color Key

Below are non-interactive mockups just to suggest the look for a user interface.

• Links do not work.
• The color key image should be centered (I could not get it centered in the mockup).
• [✓] represents a checkbox. When checked, it will color the chain by conservation, and spacefill it. When unchecked, that chain will become a gray backbone trace.
• The link to Explanation would go to a Proteopedia page of explanation. It might be a revised version of Conservation, Evolutionary.

Before expanding this section, it could look like this:

Evolutionary Conservation:                           [show]

After expanding, it could look like this:

Evolutionary Conservation:                           [hide]
Show Conservation for Chain(s):	Rows = identical sequences:  [✓]A [✓]B  [✓]C [✓]D
Further Information:	Explanation Complete results at ConSurf

Scripts