1z7k
From Proteopedia
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Crystal Structure of Trypsin- Ovomucoid turkey egg white inhibitor complex
Overview
Crystal structure of the complex between porcine beta-trypsin and the, second domain of the Kazal-type ovomucoid turkey egg white trypsin, inhibitor (OMTKY2) has been determined at 1.9A resolution. A peptide, fragment from the first domain has been crystallized with the complex., Restrained-refinement of the structure led to an R-factor of 0.19 for the, 32206 reflections. OMTKY2 exhibits the canonical Kazal-type fold with a, central alpha-helix and a short two-stranded anti-parallel beta-sheet. The, carbonyl carbon of the reactive site prefers trigonal geometry. The, reactive site loop geometry of the inhibitor is complementary to the, surface and charge of the binding site in beta-trypsin.
About this Structure
1Z7K is a Protein complex structure of sequences from Meleagris gallopavo and Sus scrofa. This structure superseeds the now removed PDB entry 1R0T. Active as Trypsin, with EC number 3.4.21.4 Full crystallographic information is available from OCA.
Reference
Crystal structure of trypsin-turkey egg white inhibitor complex., Ibrahim BS, Pattabhi V, Biochem Biophys Res Commun. 2004 Jan 2;313(1):8-16. PMID:14672690
Page seeded by OCA on Wed Nov 21 07:16:58 2007
