1qcq

Structural highlights

Function

UBC4_YEAST Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Mediates ubiquitination of PEX5.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

• 3D structures of ubiquitin conjugating enzyme

References

1. ↑ Williams C, van den Berg M, Sprenger RR, Distel B. A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p. J Biol Chem. 2007 Aug 3;282(31):22534-43. Epub 2007 Jun 5. PMID:17550898 doi:http://dx.doi.org/10.1074/jbc.M702038200