Image:Caspase mediated apoptosis.PNG
From Proteopedia
No higher resolution available.
Caspase_mediated_apoptosis.PNG (539 × 479 pixel, file size: 51 KB, MIME type: image/png)
Summary
Pathway 1: Tumor necrosis factor induces the upstream initiator caspases, caspase 8 and 9, Caspase 8 and 9 activate the downstream executioners, caspase 3,6 and 7, then they cleave upwards of 500 key proteins and DNA, which cause the apoptosis. Pathway 2: Tumor necrosis factor induces Mitochondria, which release cytochrome c to bind to apoptotic protease activating factor 1. Then the complex activates pro-caspase 9, which will activate caspase 9 to activate caspase 3 and finally lead the apoptosis.
Licensing
I, the copyright holder of this work, hereby release it into the public domain. This applies worldwide.In case this is not legally possible,
I grant any entity the right to use this work for any purpose, without any conditions, unless such conditions are required by law.
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | User | Dimensions | File size | Comment | |
---|---|---|---|---|---|
(current) | 04:25, 17 April 2012 | Student (Talk | contribs) | 539×479 | 51 KB | Pathway 1: Tumor necrosis factor induces the upstream initiator caspases, caspase 8 and 9, Caspase 8 and 9 activate the downstream executioners, caspase 3,6 and 7, then they cleave upwards of 500 key proteins and DNA, which cause the apoptosis. Pathway 2 |
- Edit this file using an external application
See the setup instructions for more information.
Links
The following pages link to this file: