Structural highlights
3h5f is a 3 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | X-ray diffraction, Resolution 1.86Å |
| Ligands: | , , , , , |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Publication Abstract from PubMed
The effects of switching the chirality of a single layer of amino acids in a three stranded coiled coil has been investigated. X-ray crystallography reveals that this modification is well tolerated and does not alter the designed structure. In contrast, spectroscopic studies of cadmium binding to both the L- and D- enantiomers of the penicillamine, provide evidence that this switch dramatically alters the metal binding capability, the resulting coordination environment and the position of binding.
Switching the chirality of the metal environment alters the coordination mode in designed peptides.,Peacock AF, Stuckey JA, Pecoraro VL Angew Chem Int Ed Engl. 2009;48(40):7371-4. doi: 10.1002/anie.200902166. PMID:19579245[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Peacock AF, Stuckey JA, Pecoraro VL. Switching the chirality of the metal environment alters the coordination mode in designed peptides. Angew Chem Int Ed Engl. 2009;48(40):7371-4. PMID:19579245 doi:10.1002/anie.200902166
