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Article title matches

  1. Image:Imatinib bound to receptor.PNG (933 bytes)
    4: ...ear explanation for the impressive selectivity of imatinib could be found
  2. Category:Imatinib (39 bytes)
    1: List of pages with the keyword Imatinib
  3. Category:Imatinib complex (47 bytes)
    1: List of pages with the keyword Imatinib complex
  4. Category:Imatinib resistance (50 bytes)
    1: List of pages with the keyword Imatinib resistance
  5. Bcr-Abl and Imatinib (STI571 or Gleevec) (24,270 bytes)
    5: See also [[Imatinib]]
    99: ...867/Cv/2'>Human Abl kinase domain in complex with imatinib</scene>
    102: ...e:Imatinib_bound_to_receptor.PNG|thumb|400px|left|Imatinib]]
    104: ...Abl TKI) with a high affinity for the ABL kinase. Imatinib is the most common first generation drug used for...
    105: ...n and loss of viability.<ref>PMID:16783341</ref>. Imatinib also inhibits the Abl protein of non-cancer cells...
  6. Imatinib (4,613 bytes)
    1: ...side='right' scene='Imatinib/Imatinib/2' caption='Imatinib, also known as Gleevec ([[2hyy]])' pspeed='8'>
    10: * See also [[Bcr-Abl and Imatinib (STI571 or Gleevec)]]
    14: ...> In BCR-Abl, <scene name='Imatinib/Bound_imat/7'>Imatinib is bound</scene> by H-bonds to residues Met 318, ...

Page text matches

  1. 3zos (4,059 bytes)
    14: ...fore accommodated outside the ATP pocket. Whereas imatinib and ponatinib bind potently to both the DDR and A...
  2. 2v7a (8,542 bytes)
    26: ...tion Bcr-Abl inhibitors are able to overcome most imatinib-resistant mutants, with the exception of the freq...
  3. 2z60 (6,878 bytes)
    24: ...utation. In contrast to other inhibitors, such as imatinib and dasatinib, PPY-A does not occupy the hydropho...
  4. 1opl (8,297 bytes)
    26: ... differential ability of the drug STI-571/Gleevec/imatinib (STI-571) to inhibit the catalytic activity of Ab...
  5. 2g1t (8,305 bytes)
    26: ...inactive Src-like conformation than the active or imatinib-bound conformations. Our results suggest that int...
  6. 2g2f (8,336 bytes)
    26: ...inactive Src-like conformation than the active or imatinib-bound conformations. Our results suggest that int...
  7. 2g2h (8,278 bytes)
    26: ...inactive Src-like conformation than the active or imatinib-bound conformations. Our results suggest that int...
  8. 2g2i (8,206 bytes)
    26: ...inactive Src-like conformation than the active or imatinib-bound conformations. Our results suggest that int...
  9. 2gqg (8,720 bytes)
    28: ...explanation for the activity of dasatinib against imatinib-resistant BCR-ABL mutants.
    30: ...domain elucidates its inhibitory activity against imatinib-resistant ABL mutants.,Tokarski JS, Newitt JA, Ch...
  10. 2hyy (8,114 bytes)
    2: ==Human Abl kinase domain in complex with imatinib (STI571, Glivec)==
    26: ...f wild-type and mutant Abl kinase in complex with imatinib and other small-molecule Abl inhibitors were dete...
  11. 2hz0 (8,087 bytes)
    26: ...f wild-type and mutant Abl kinase in complex with imatinib and other small-molecule Abl inhibitors were dete...
  12. 2pl0 (4,553 bytes)
    2: ==LCK bound to imatinib==
  13. 1iep (7,187 bytes)
    24: ...omain of Abl in complex with two such inhibitors, imatinib (also known as STI-571 and Gleevec) and PD173955 ...
    26: ...x with the small molecule inhibitors PD173955 and imatinib (STI-571).,Nagar B, Bornmann WG, Pellicena P, Sch...
  14. Image:Imatinib bound to receptor.PNG (933 bytes)
    4: ...ear explanation for the impressive selectivity of imatinib could be found
  15. 1opk (6,666 bytes)
    24: ... differential ability of the drug STI-571/Gleevec/imatinib (STI-571) to inhibit the catalytic activity of Ab...
  16. 1t45 (7,351 bytes)
    25: ...ystal structure of c-Kit in complex with STI-571 (Imatinib or Gleevec) demonstrates that inhibitor binding d...
  17. 2f4j (8,815 bytes)
    2: ==Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora K...
    26: ...stabilizes the inactive conformation required for imatinib binding, and the binding of VX-680, which favors ...
    28: Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora k...
  18. 2hzn (6,729 bytes)
    24: ...f wild-type and mutant Abl kinase in complex with imatinib and other small-molecule Abl inhibitors were dete...
  19. 2oiq (6,055 bytes)
    2: ...Src kinase domain in complex with the cancer drug imatinib.==
    24: ...nce between different inactive states is a key to imatinib binding.
    26: c-Src binds to the cancer drug imatinib with an inactive Abl/c-Kit conformation and a dis...
  20. 2qoh (6,858 bytes)
    24: ...utation. In contrast to other inhibitors, such as imatinib and dasatinib, PPY-A does not occupy the hydropho...

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