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- Image:Inhib.jpg (0 bytes)
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- 9eqh (3,898 bytes)
11: ...asomal degradation; in T-cells the ubiquitination inhibits activation-induced cell death. Ubiquitinates S...
14: ...ancers and diseases. Here we expand their limited inhibitor space by identification of NSC-217913 display...
16: ...son GR, Storr TE, Chantry A, Hemmings AM J Enzyme Inhib Med Chem. 2024 Dec;39(1):2394895. doi: , 10.1080/... - 9eqk (3,681 bytes)
13: ...ancers and diseases. Here we expand their limited inhibitor space by identification of NSC-217913 display...
15: ...son GR, Storr TE, Chantry A, Hemmings AM J Enzyme Inhib Med Chem. 2024 Dec;39(1):2394895. doi: , 10.1080/... - 9b2e (3,802 bytes)
2: ==DHNA associated with an inhibitor==
14: ...herein will advance the quest for novel, specific inhibitors targeting MtFolB, an attractive molecular ta...
16: ...Moura S, Machado P, Bizarro CV, Basso LA J Enzyme Inhib Med Chem. 2024 Dec;39(1):2388207. doi: , 10.1080/... - 3zj6 (3,707 bytes)
2: ...stal of Raucaffricine Glucosidase in complex with inhibitor==
14: ... A distance will enable the development of potent inhibitors suitable for the production of valuable alka...
16: ... Wang M, Warzecha H, Jager V, Stockigt J J Enzyme Inhib Med Chem. 2014 Aug 20:1-7. PMID:25140865<ref>PMID... - 3zj7 (3,658 bytes)
2: ...ture of strictosidine glucosidase in complex with inhibitor-1==
14: ... A distance will enable the development of potent inhibitors suitable for the production of valuable alka...
16: ... Wang M, Warzecha H, Jager V, Stockigt J J Enzyme Inhib Med Chem. 2014 Aug 20:1-7. PMID:25140865<ref>PMID... - 3zj8 (3,670 bytes)
2: ...ture of strictosidine glucosidase in complex with inhibitor-2==
14: ... A distance will enable the development of potent inhibitors suitable for the production of valuable alka...
16: ... Wang M, Warzecha H, Jager V, Stockigt J J Enzyme Inhib Med Chem. 2014 Aug 20:1-7. PMID:25140865<ref>PMID... - 3hlj (5,692 bytes)
26: .... Some of the compounds studied are submicromolar inhibitors of the isoform IX, a prominent cancer target...
28: ...sca A, Supuran CT, Grazulis S, Matulis D J Enzyme Inhib Med Chem. 2010 Feb 18. PMID:20166809<ref>PMID:201... - Phosphofructokinase (PFK) (15,891 bytes)
7: ...hey promote the formation of the T state, thereby inhibiting the enzyme.
17: ...phosphofructokinase. Along with ADP,AMP and F2,6P inhibit the regulatory role of ATP.
23: [[Image:Paint_image.JPG]]
27: [[Image:Inhib.jpg]]
29: ...olds true as well, because high ATP concentration inhibits protein activity. And yet, this explanation ca... - Cassady sandbox1 (7,020 bytes)
11: [[Image:Subunit.JPG]]
16: [[Image:PFK mech.JPG]]
21: [[Image:Paint_image.JPG]]
25: [[Image:Inhib.jpg]]
27: ...olds true as well, because high ATP concentration inhibits protein activity. And yet, this explanation ca... - 3tne (3,301 bytes)
2: ...ida parapsilosis in complex with the HIV protease inhibitor ritonavir==
14: ...uate the stability and specificity of the protein-inhibitor interaction.
16: ...eldova O, Pachl P, Pichova I, Rezacova P J Enzyme Inhib Med Chem. 2012 Feb;27(1):160-5. Epub 2011 Dec 6. ... - 8bzz (4,678 bytes)
16: ...) CA II pointing out the binding site and mode of inhibition of this class of CAIs. The thorough comprehe...
18: ...ni M, Bonardi A, Supuran CT, Nocentini A J Enzyme Inhib Med Chem. 2023 Dec;38(1):2178430. doi: , 10.1080/... - 4mum (3,617 bytes)
16: ...Fabry M, Veverka V, Brynda J, Rezacova P J Enzyme Inhib Med Chem. 2014 Feb 10. PMID:24506201<ref>PMID:245... - 3wqh (4,574 bytes)
11: ...expressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase w...
16: ... Okada S, Motoyama T, Takahashi R, Oka M J Enzyme Inhib Med Chem. 2015 Jul 6:1-8. PMID:26147347<ref>PMID:... - 8i7p (3,499 bytes)
12: ...Tyr80 and Asn122 are responsible for the high RTA inhibitory activity of 7PCGY.
14: ... Higashi S, Kawata R, Nagatsu K, Saito R J Enzyme Inhib Med Chem. 2023 Dec;38(1):2219038. doi: , 10.1080/... - 4tq8 (7,332 bytes)
16: ...fferently substituted mono-aryl compounds able to inhibit TTR fibril formation.
18: ...sello A, Tepshi L, Stura EA, Orlandini E J Enzyme Inhib Med Chem. 2015 Aug 3:1-10. PMID:26235916<ref>PMID... - 4tqh (7,309 bytes)
16: ...fferently substituted mono-aryl compounds able to inhibit TTR fibril formation.
18: ...sello A, Tepshi L, Stura EA, Orlandini E J Enzyme Inhib Med Chem. 2015 Aug 3:1-10. PMID:26235916<ref>PMID... - 4tqi (7,345 bytes)
16: ...fferently substituted mono-aryl compounds able to inhibit TTR fibril formation.
18: ...sello A, Tepshi L, Stura EA, Orlandini E J Enzyme Inhib Med Chem. 2015 Aug 3:1-10. PMID:26235916<ref>PMID... - 4tqp (7,392 bytes)
16: ...fferently substituted mono-aryl compounds able to inhibit TTR fibril formation.
18: ...sello A, Tepshi L, Stura EA, Orlandini E J Enzyme Inhib Med Chem. 2015 Aug 3:1-10. PMID:26235916<ref>PMID... - 5e23 (7,291 bytes)
16: ...erent potency. Of these compounds, 2c is the best inhibitor. The dual binding mode prevalent in the absen...
18: ...tti S, Rossello A, Stura EA, Orlandini E J Enzyme Inhib Med Chem. 2016 Apr 11:1-12. PMID:27067161<ref>PMI... - 5e4a (7,234 bytes)
16: ...erent potency. Of these compounds, 2c is the best inhibitor. The dual binding mode prevalent in the absen...
18: ...tti S, Rossello A, Stura EA, Orlandini E J Enzyme Inhib Med Chem. 2016 Apr 11:1-12. PMID:27067161<ref>PMI...
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