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Membrane proteins
From Proteopedia
Contents |
Proteopedia Articles
- Receptor#Transmembrane (cell surface) receptors
- Photosystem II
- Escherichia coli GlpG, an integral membrane protein rhomboid protease, unique in cleaving the transmembrane domains of other membrane proteins, 2ic8.
- Ion channels
- Pore forming toxin, α-hemolysin
- Urea transporter
- Glutamate receptor
- G protein-coupled receptors
- A Physical Model of the β2-Adrenergic Receptor
Technical Issues
See Also
External Resources
- Li F, Egea PF, Vecchio AJ, Asial I, Gupta M, Paulino J, Bajaj R, Dickinson MS, Ferguson-Miller S, Monk BC, Stroud RM. Highlighting membrane protein structure and function: A celebration of the Protein Data Bank. J Biol Chem. 2021 Jan-Jun;296:100557. doi: 10.1016/j.jbc.2021.100557. Epub 2021, Mar 18. PMID:33744283 doi:http://dx.doi.org/10.1016/j.jbc.2021.100557
- Membrane Proteins of Known 3D Structure (from the Stephen White laboratory at Univ. California, Irvine, USA).
- Membrane Proteins of Known Structure (from Max Planck Institute in Frankfurt, Germany) not updated since 2006 but useful for tabulation of crystallization conditions.
- Orientations of Proteins in Membranes (OPM) database (University of Michigan, USA) features calculated membrane boundaries for all membrane proteins in the PDB.
- MemProtMD - A database of membrane proteins embedded in lipid bilayers features a database of over 5000 intrinsic membrane protein structures identified in the Protein Data Bank, inserted into simulated lipid bilayers using Coarse-Grained Self Assembly Molecular Dynamics simulations. A few of the MemProtMD workflows have been put together as a set of Google Colab notebooks for establishing membrane protein structures in bilayers, see here.
- The PSIPRED Protein Structure Prediction Server has a highly accurate method for protein secondary structure prediction for proteins without an empirically-determined 3D structure and features also a widely used transmembrane topology prediction method where the output includes a Kyte-Doolittle Hydropathy Plot.
- von Heijne G. Membrane-protein topology. Nat Rev Mol Cell Biol. 2006 Dec;7(12):909-18. PMID:17139331 doi:10.1038/nrm2063
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Wayne Decatur, Eric Martz, Alexander Berchansky, Nikki Hunter, Jaime Prilusky, David Canner
