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- Image:Ospb 2.jpg (0 bytes)
- User:Marvin O'Neal/OspB (9,076 bytes)
1: ... transmission from the tick to a vertebrate host, OspB is downregulated and other proteins such as OspC,...
4: ...l' size='450' frame='true' align='right' caption='OspB interacting with Fab H6831' scene='User:Olivia_Ch...
6: ... outer surface proteins found on ''B. Borrelia''. OspB has shown significant variability in amino acid s...
8: = OspB Interaction with Fab of H6831 =
11: ...1rjl_chainc_transparentabd/6'>a truncated form of OspB</scene>, shown in purple. The H6831 Fab is shown ... - User:Marvin O'Neal/Antibody OspA and OspB (10,093 bytes)
4: ...eir corresponding outer surface protein (OspA and OspB) of ''B. burgdoferi'' leads to the lysis of the b...
8: ...d CB2 are IgG mAbs that targets the C-terminal of OspB and LA-2 is an IgM mAb that targets the C-termina...
25: ==OspB and H6831==
26: ... /></td></tr><tr><td bgcolor='#eeeeee'><center>'''OspB-H6831 Complex''' (<scene name='Studio:G1SecL01/1/...
27: <scene name='Studio:G1SecL01/1/11'>OspB</scene>''':''' <scene name='Studio:G1SecL01/1/31'... - Outer surface protein B (OspB) of the Lyme disease spirochete bacterium (7,857 bytes)
1: ...ite [[1rjl]]' scene='User:Konrad_Surdel/Workbench/Ospb1/6' />
5: ...causative agent of Lyme disease. The functions of OspB are not yet fully known or understood, though it ...
8: ...acilitating movement from the vector to the host. OspB also has a highly conserved region of hydrophobic...
9: ...dy it could potentially be due to some feature of OspB.
12: ...formational differences between bound and unbound OspB. In the bound form, strands of a beta-sheet were ... - Image:Antibody ospb.png (0 bytes)
Page text matches
- G09SecL04Tpc2 (14,557 bytes)
8: ...dia.org/wiki/Lipoprotein lipoproteins], including OspB, OspC, and Vls (see 3-D Structures below), which ...
62: *[http://www.proteopedia.org/wiki/index.php/1rjl OspB] - G14secL04Tpc3 (12,005 bytes)
1: ...size='350' side='right' scene='G14secL04Tpc3/Free_ospb_colored/2' caption='Lyme disease spirochete outer...
3: == Lyme Disease and OspB protein==
11: ...uctural Investigation of ''Borrelia burgdorferi'' OspB, a Bactericidal Fab Target. The Journal of Biolog...
17: ...regulated <ref name="transmit" />. Since OspA and OspB are critical for the adherence of the spirochet...
19: ==Free OspB structure== - 2b1w (2,916 bytes)
10: ...F-kappa-B by Shigella effector proteins IpgB2 and OspB. Recruits NLRP10 to the cell membrane following b... - 2dbd (3,017 bytes)
10: ...F-kappa-B by Shigella effector proteins IpgB2 and OspB. Recruits NLRP10 to the cell membrane following b... - 2nsn (3,628 bytes)
10: ...F-kappa-B by Shigella effector proteins IpgB2 and OspB. Recruits NLRP10 to the cell membrane following b... - G13secL03Tpc3 (4,532 bytes)
9: ...e='true' align='right' scene='G13secL03Tpc3/Final_ospb/2'/>
16: ...butes most to the contact and binding of H6831 to OspB.
19: ...ng the bactericidal Fab complex is the removal of OspB's first four beta sheets. Surrounding sheets shif...
25: ...e disease. Vaccines created to specifically fight OspB have not yet been successful, due to the increase... - 1rjl (4,242 bytes)
2: ==Structure of the complex between OspB-CT and bactericidal Fab-H6831==
10: [https://www.uniprot.org/uniprot/OSPB_BORBU OSPB_BORBU]
23: ...l dimers connected by intermolecular beta-sheets. OspB structure, stability, and possible mechanisms of ...
25: Structural investigation of Borrelia burgdorferi OspB, a bactericidal Fab target.,Becker M, Bunikis J, ... - G12SecL02Tpc3 (2,844 bytes)
2: ... lipid anchored outer surface proteins, including OspB.
4: ...crobes without help from WBCs. Recognition of the OspB epitope by either antibody is dependent on the ly...
6: ...that the protein dimerizes with perfect symmetry. OspB contains 12 anti-parallel strands and one α- hel...
7: ... to solvent when the protein is uncomplexed. When OspB is complexed however, Lys253 has extensive intera...
9: ...kely that this structure play a role in anchoring OspB to the lipid membrane. It is most likely proteoly... - 1p4p (4,043 bytes)
10: [https://www.uniprot.org/uniprot/OSPB_BORBU OSPB_BORBU]
23: ...l dimers connected by intermolecular beta-sheets. OspB structure, stability, and possible mechanisms of ...
25: Structural investigation of Borrelia burgdorferi OspB, a bactericidal Fab target.,Becker M, Bunikis J, ... - 1ry9 (2,805 bytes)
11: ...to chaperone IpaA, IpgB1, OspC3 and probably also OspB. - G04SecL04Tpc1 (8,068 bytes)
5: Outer surface protein B (OspB) combines with a bactericidal fab H6831 in order ...
7: ...L' size='300' frame='true' align='right' caption='OspB and Fab complex' scene='G04SecL04Tpc1/1rjl/1' />
21: === Comparison between OspB-H6831 and OspA-LA2===
27: ...d surface area of OspA in LA-2 Fab is larger than OspB in the H6831Fab<ref name="Becker M">PMID:15713683...
37: ...gh the exact mechanism of the bacterial effect of OspB and Fab H6831 complex is not know there are sever... - Outer surface protein (2,647 bytes)
3: ... burgdorferi which causes Lyme disease. OspA and OspB are upregulated when the bacteria enter the tick....
6: * '''OspB'''<ref>PMID:17352535</ref>, '''OspC'''<ref>PMID:2...
12: OspB - <br />
13: *[[Outer surface protein B (OspB) of the Lyme disease spirochete bacterium]]<br />
23: OxpA, OspB and OspC - <br /> - 2nz7 (3,631 bytes)
10: ...F-kappa-B by Shigella effector proteins IpgB2 and OspB. Recruits NLRP10 to the cell membrane following b... - Sandbox1 (18,119 bytes)
11: ...8OspB%29_of_the_Lyme_disease_spirochete_bacterium OspB], and [http://proteopedia.org/wiki/index.php/User...
63: [[Image:G2L03-OspA-mechanism.jpg|thumb|300px|Mechanism of the host inflammatory re...
94: ...ins in the treatment of Lyme disease than that of OspB. The first vaccine used a purified recombinant fo... - User:Sobia Rafiuddin/Sandbox1 (287 bytes)
8: ...scene name='User:Sobia_Rafiuddin/Sandbox1/Ospb/1'>OspB</scene> - G18secL03Tpc4 (12,268 bytes)
4: ..., respectively). It greatly differs from OspA and OspB in both structure and function. The uniqueness of...
10: ...ue when compared to its sister proteins, OspA and OspB, which are made up of beta-sheets mostly.<ref nam...
19: ...ectin, in a process that does not require OspA or OspB.<ref>PMID:10072447</ref>
45: [http://www.proteopedia.org/wiki/index.php/OspB OspB]
51: ....org/wiki/index.php/Image:OspC_electro_potentials.jpg OspC Electro Potentials] - 2xga (3,410 bytes)
11: ...to chaperone IpaA, IpgB1, OspC3 and probably also OspB. - User:Marvin O'Neal/OspA (20,364 bytes)
47: [[Image:G2L03-OspA-mechanism.jpg|thumb|300px|Mechanism of the host inflammatory re...
78: ...ins in the treatment of Lyme disease than that of OspB. The first vaccine used a purified recombinant fo... - User:Marvin O'Neal/OspB (9,076 bytes)
1: ... transmission from the tick to a vertebrate host, OspB is downregulated and other proteins such as OspC,...
4: ...l' size='450' frame='true' align='right' caption='OspB interacting with Fab H6831' scene='User:Olivia_Ch...
6: ... outer surface proteins found on ''B. Borrelia''. OspB has shown significant variability in amino acid s...
8: = OspB Interaction with Fab of H6831 =
11: ...1rjl_chainc_transparentabd/6'>a truncated form of OspB</scene>, shown in purple. The H6831 Fab is shown ... - User:Marvin O'Neal/OspC (14,368 bytes)
4: ...nthesis and inhibiting the expression of OspA and OspB due to changes in environmental temperature and p...
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