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Article title matches
- Category:Pi3k (35 bytes)
1: List of pages with the keyword Pi3k - Category:Pi3k gamma (41 bytes)
1: List of pages with the keyword Pi3k gamma - Category:Class 2 pi3k (43 bytes)
1: List of pages with the keyword Class 2 pi3k - Category:P85beta subunit of pi3k (54 bytes)
1: List of pages with the keyword P85beta subunit of pi3k - Category:Pi3k-gamma p110 gamma (52 bytes)
1: List of pages with the keyword Pi3k-gamma p110 gamma - Category:Pi3k class iii (45 bytes)
1: List of pages with the keyword Pi3k class iii - PI3K (39 bytes)
- Image:PI3K Complex.pdb (0 bytes)
- Image:PI3K yea.pdb (0 bytes)
- Image:PI3K Complex 2.pdb.gz (0 bytes)
- Structure of PI3K (34 bytes)
1: #REDIRECT[[The Structure of PI3K]] - PI3K Activation (64 bytes)
1: #REDIRECT[[PI3K Activation, Inhibition, & Medical Implications]] - PI3K Inhibition (64 bytes)
1: #REDIRECT[[PI3K Activation, Inhibition, & Medical Implications]] - PI3K Medical Implications (64 bytes)
1: #REDIRECT[[PI3K Activation, Inhibition, & Medical Implications]] - PI3K Inhibition and Medical Implications (64 bytes)
1: #REDIRECT[[PI3K Activation, Inhibition, & Medical Implications]] - PI3K Activation, Inhibition, and Medical Implications (64 bytes)
1: #REDIRECT[[PI3K Activation, Inhibition, & Medical Implications]] - PI3K Activation, Inhibition, & Medical Implications (8,395 bytes)
1: ==Activation of Class IA PI3K==
2: ...interact with PI3K regulatory subunits like nSH2. PI3K can be additionally activated in cooperative proc...
5: ==PI3K Inhibition==
6: ...id_Canner/Sandbox_P/Full/4' caption='Structure of PI3K p110, ([[3hhm]])'>
8: ...iles are currently in clinical trials for various PI3K associated diseases. <ref>PMID: 1474947</ref> - PI3K Structure (34 bytes)
1: #REDIRECT[[The Structure of PI3K]] - The Structure of PI3K (10,399 bytes)
1: ==Structure of PI3K==
2: Class I [[PI3K|PI3Ks]], which are tightly regulated by tyrosine kinas...
6: ...id_Canner/Sandbox_P/Full/4' caption='Structure of PI3K p110, ([[3hhm]])'>
8: ...aneously, allowing for significant fine tuning of PI3K activity. <ref name="Wymann"> PMID: 9838078</ref>
11: ...r/Sandbox_P/Sh3_network_open/1'>The SH3 domain of PI3K</scene> has homologues found in many intracellula... - PI3K/AKT/mTOR signaling pathway (1,012 bytes)
1: ...='3hhm' size='350' side='right' scene='' caption='PI3K (grey) complex with NISH2 P85α and wortmannin (P...
2: ...iescence, proliferation, cancer, and longevity. [[PI3K]] activation phosphorylates and activates AKT, lo...
Page text matches
- 1e7v (6,570 bytes)
11: ... is assembled in a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which i...
24: ... a rich basis for development of isoform-specific PI3K inhibitors with therapeutic potential. - 1e7u (6,640 bytes)
11: ... is assembled in a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which i...
24: ... a rich basis for development of isoform-specific PI3K inhibitors with therapeutic potential. - 1e8z (6,812 bytes)
11: ... is assembled in a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which i...
24: ... a rich basis for development of isoform-specific PI3K inhibitors with therapeutic potential. - 1e8w (6,557 bytes)
11: ... is assembled in a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which i...
24: ... a rich basis for development of isoform-specific PI3K inhibitors with therapeutic potential. - 9c15 (8,152 bytes)
13: ...3CA_HUMAN PK3CA_HUMAN] Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol...
16: ...activation and provides a blueprint for designing PI3Kalpha isoform-specific inhibitors to disrupt this ...
18: ...RAS-PI3Kalpha interactions and the role of RAS in PI3Kalpha activation.,Czyzyk D, Yan W, Messing S, Gill... - 2uzi (7,478 bytes)
26: ... protein interaction with effector proteins, like PI3K, RAF and RALGDS. Such protein interactions are th... - 2iwi (6,280 bytes)
11: ...mTORC1)-independent manner and in parallel to the PI3K-Akt pathway. Mediates survival signaling through ... - 2iwl (6,254 bytes)
24: ... and thereby mediates the membrane recruitment of PI3K-C2alpha. - 9ivb (5,092 bytes)
13: ...s associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embry... - 1e90 (6,588 bytes)
11: ... is assembled in a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which i...
24: ... a rich basis for development of isoform-specific PI3K inhibitors with therapeutic potential. - 1a25 (6,955 bytes)
11: ...ed VEGFA-induced cell proliferation, and inhibits PI3K/AKT-dependent nitric oxide synthase (NOS3/eNOS) r... - 1unr (12,070 bytes)
26: ...mediated activation of phosphoinositide 3-kinase (PI3K). The binding of PKB to PtdIns(3,4,5)P3/PtdIns(3,... - 1unq (12,143 bytes)
26: ...mediated activation of phosphoinositide 3-kinase (PI3K). The binding of PKB to PtdIns(3,4,5)P3/PtdIns(3,... - 2chx (7,173 bytes)
11: ... is assembled in a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which i... - 2chz (7,177 bytes)
11: ... is assembled in a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which i... - 2chw (7,182 bytes)
11: ... is assembled in a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which i... - 1he8 (7,609 bytes)
26: ...alpha. The complex with Ras shows a change in the PI3K conformation that may represent an allosteric com... - 8twy (5,854 bytes)
12: ...3CA_HUMAN PK3CA_HUMAN] Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol... - 1avv (8,828 bytes)
10: ...omplex 1) or possibly Src family kinase-ZAP70/Syk-PI3K cascade recruited by PACS2. In consequence infect... - 1avz (8,997 bytes)
10: ...omplex 1) or possibly Src family kinase-ZAP70/Syk-PI3K cascade recruited by PACS2. In consequence infect...
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