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- Image:R1441.jpg (69 bytes)
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- 2zej (6,241 bytes)
26: ... monomers. Two PD-associated pathogenic residues, R1441 and I1371, are located at the interface of two mo... - 3d6t (6,244 bytes)
26: ... monomers. Two PD-associated pathogenic residues, R1441 and I1371, are located at the interface of two mo... - Student Project 5 for UMass Chemistry 423 Spring 2015 (14,775 bytes)
69: [[Image:Binding pocket 4py1.jpg|left|300px]]
95: ...t color='9400D3'> '''guanidine group'''</font> of R1441 exhibits essential <scene name='48/483886/Roc_dim...
98: ..., and other important interactions contributed by R1441 and I1371, mutations of either residue can easily... - LRRK2 (5,660 bytes)
3: [[Image:fulllengthLRRK2model.jpg|300px|right|thumb|Top and bottom view of dimeric ...
12: ... LRRK2 mutations that are proven to cause PD, the R1441 is the second most common, and it was found to be...
13: [[Image:R1441.jpg|300px|right|thumb|The residue R1441 is located at the end of helix α3 and interacts ...
15: == Mechanism of action of R1441C mutation ==
16: ...cleotide being more effective in this regard. The R1441C mutation affects the stability of the ROC domain...
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