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- Category:Titin (36 bytes)
1: List of pages with the keyword Titin - Image:Titin-t.jpg (43 bytes)
- Image:TITIN-Z1Z2 strechend unstreched.jpg (37 bytes)
- Titin Structure & Function (5,427 bytes)
1: ...3' size='400' side='right' scene= caption='Rabbit titin molecule I65-I70 [[3b43]]' >
4: ...rgest proteins known today.<ref name=journal4/> Titins are a family of large proteins that which can be...
8: ...s the overlapped carboxyl terminus regions of the titin molecule. <ref name=journal1/> The Z-line region...
13: ...=journal3>PMID:18212128</ref>. In mature muscle, titin molecules is to take part in the mechanisms that ...
15: ...ld be mutations that affect the I-band portion of titin would change the elasticity of muscle.<ref name=j... - Titin (7,066 bytes)
1: ...tureSection load="1ya5" size="350" caption="Human titin dimer residues 1-196 (grey and pale green) comple...
3: ... is stretched. <scene name='41/417484/Cv/1'>Human titin dimer residues 1-196 complex with telethonin</sce...
4: *[[Titin Structure & Function]]<br />
5: *[[Group:MUZIC:Titin]].
7: [[Image:2a38 bio assembly1.jpg|225px]] - Group:MUZIC:Titin (27,074 bytes)
3: ...et al''., 1977 <ref> Maruyama K. (1997) Connectin/titin, giant elastic protein of muscle. FASEB J. 11(5):...
4: ...</ref> domains <ref> Labeit S, Kolmerer B. (1995) Titins: giant proteins in charge of muscle ultrastructu...
5: ...2000) Stretching molecular springs: elasticity of titin filaments in vertebrate striated muscle. Histol H...
7: ...itment of the ubiquitin-ligase MuRF-1 onto M-line titin. FASEB J. 21(7):1383-92. Epub 2007 Jan 10.PMID 17...
8: ... Tskhovrebova L, Trinick J. (2004) Properties of titin immunoglobulin and fibronectin-3 domains. J Biol ... - Category:Immuno pmhc tcr titin (52 bytes)
1: List of pages with the keyword Immuno pmhc tcr titin - Category:Titin i27 domain (47 bytes)
1: List of pages with the keyword Titin i27 domain - User:Chris Garcia/Characteristics of Titin (6,950 bytes)
1: ==The Titin 1ya5 with Z1Z2 domain==
4: ...ctin repeats, and flexible coil PEVK. Isoforms of titin from insertions of single Ig-domains can be found...
6: ... that these different types of domains within the titin spring determine the stiffness and extensibility ...
8: ...ing prevents our muscles from over stretching. “Titin I27 is the first structurally determined Ig domai...
9: ...ges. The molecular structure of an Ig fold allows titin to bear an immense amount of mechanical stress. - User:Chris Garcia/Titin Z1Z2 complex (7,729 bytes)
1: ==The Titin 1ya5 with Z1Z2 domain==
4: ...ctin repeats, and flexible coil PEVK. Isoforms of titin from insertions of single Ig-domains can be found...
6: ... that these different types of domains within the titin spring determine the stiffness and extensibility ...
8: ...vides a major role in the stability of N-terminal titin at the Z-line. Towards the carboxy-terminal in th...
17: ...nk L., and Siegfried Labeit. “The Giant Protein Titin.” Circulation Research, vol. 94, no. 3, 2004, p... - Image:Titin.JPG (0 bytes)
- Titin 3D structures (2,808 bytes)
1: == 3D Structures of Titin == - Image:Titin isoforms.PNG (88 bytes)
2: Table of titin isoform structural differences. - Titin related diseases (11,528 bytes)
1: == Titin ==
2: ...43' size='340' side='right' caption='A segment of Titin, showing six IG domains (PDB code [[3b43]])' scen...
7: '''Titin''', which is also known as connectin, is the larg...
11: Titin is a very large protein, comprising 244 individua...
12: The protein titin has thirteen different isoforms in human striated...
Page text matches
- 1waa (7,638 bytes)
11: ...e TTN deletions, which lead to a total absence of titin's C-terminal end from striated muscles and to sec...
13: [https://www.uniprot.org/uniprot/TITIN_HUMAN TITIN_HUMAN] Key component in the assembly and function...
26: ...mined high-resolution crystal structure of I27, a titin immunoglobulin (IG) domain. We obtain a sparse, s...
28: Mechanical network in titin immunoglobulin from force distribution analysis.,...
35: *[[Titin 3D structures|Titin 3D structures]] - 2bkf (2,749 bytes)
14: ...ral perspective on the involvement of NBR1 in the titin kinase signalling pathway. - 2j8h (7,261 bytes)
2: ... of the immunoglobulin tandem repeat A168-A169 of titin==
11: ...e TTN deletions, which lead to a total absence of titin's C-terminal end from striated muscles and to sec...
13: [https://www.uniprot.org/uniprot/TITIN_HUMAN TITIN_HUMAN] Key component in the assembly and function...
26: ...this tandem for both the mechanical properties of titin and for sarcomeric signaling.
28: ...epeat in the A-band of the elastic muscle protein titin.,Muller S, Lange S, Gautel M, Wilmanns M J Mol Bi... - 2j8o (7,261 bytes)
2: ...=Structure of the immunoglobulin tandem repeat of titin A168-A169==
11: ...e TTN deletions, which lead to a total absence of titin's C-terminal end from striated muscles and to sec...
13: [https://www.uniprot.org/uniprot/TITIN_HUMAN TITIN_HUMAN] Key component in the assembly and function...
26: ...this tandem for both the mechanical properties of titin and for sarcomeric signaling.
28: ...epeat in the A-band of the elastic muscle protein titin.,Muller S, Lange S, Gautel M, Wilmanns M J Mol Bi... - Sandbox Muzic (1,567 bytes)
8: <center> '''3D structures of N-terminal part of titin or its complexes, deposited in "Protein Data Bank...
15: ...ngth telethonin in complex with the N-terminus of titin || {{PMID|16713295}}
18: |Crystal structure of the N-Terminus of titin
22: |Crystal structure of the titin domains z1z2 in complex with telethonin
26: ...EF-hands 3,4 from alpha-actinin / Z-repeat 7 from titin - 1gxe (6,122 bytes)
25: ...ability of cC5 compared to other IgI domains from titin and MyBP-C itself. The low thermodynamic stabilit... - 1h8b (4,146 bytes)
2: ...EF-hands 3,4 from alpha-actinin / Z-repeat 7 from titin==
25: ...in of alpha-actinin-2 and the seventh Z-repeat of titin. The structure of the complex is in a semi-open c...
27: ...hand domain to a novel motif in the alpha-actinin-titin complex.,Atkinson RA, Joseph C, Kelly G, Muskett ...
35: *[[Titin 3D structures|Titin 3D structures]] - 1q02 (6,337 bytes)
12: ...actor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May reg... - 1rgw (5,032 bytes)
25: ...ding surface distinct from that recognized by the titin Z repeats. ZASP PDZ structure was used to model o... - 1tnm (5,628 bytes)
2: ...LOBULIN-LIKE DOMAIN FROM THE GIANT MUSCLE PROTEIN TITIN: A NEW MEMBER OF THE I SET==
10: ...e TTN deletions, which lead to a total absence of titin's C-terminal end from striated muscles and to sec...
12: [https://www.uniprot.org/uniprot/TITIN_HUMAN TITIN_HUMAN] Key component in the assembly and function...
25: *[[Titin 3D structures|Titin 3D structures]] - 1tnn (5,628 bytes)
2: ...lobulin-like domain from the giant muscle protein titin: a new member of the I set==
10: ...e TTN deletions, which lead to a total absence of titin's C-terminal end from striated muscles and to sec...
12: [https://www.uniprot.org/uniprot/TITIN_HUMAN TITIN_HUMAN] Key component in the assembly and function...
25: *[[Titin 3D structures|Titin 3D structures]] - 1ya5 (6,253 bytes)
2: ==Crystal structure of the titin domains z1z2 in complex with telethonin==
5: ...th/index.html Molecule of the Month] feature on ''Titin'' by David Goodsell is [https://dx.doi.org/10.22...
11: ...e TTN deletions, which lead to a total absence of titin's C-terminal end from striated muscles and to sec...
13: [https://www.uniprot.org/uniprot/TITIN_HUMAN TITIN_HUMAN] Key component in the assembly and function...
27: *[[Titin|Titin]] - 2bk8 (5,648 bytes)
2: ==M1 domain from titin==
10: ...e TTN deletions, which lead to a total absence of titin's C-terminal end from striated muscles and to sec...
12: [https://www.uniprot.org/uniprot/TITIN_HUMAN TITIN_HUMAN] Key component in the assembly and function...
25: *[[Titin 3D structures|Titin 3D structures]] - 2f8v (8,010 bytes)
2: ...ngth telethonin in complex with the N-terminus of titin==
11: ...e TTN deletions, which lead to a total absence of titin's C-terminal end from striated muscles and to sec...
13: [https://www.uniprot.org/uniprot/TITIN_HUMAN TITIN_HUMAN] Key component in the assembly and function...
26: ...minal part of telethonin into the assembly of two titin/telethonin complexes.
28: Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-... - 2ill (5,817 bytes)
2: ==Anomalous substructure of Titin-A168169==
11: ...e TTN deletions, which lead to a total absence of titin's C-terminal end from striated muscles and to sec...
13: [https://www.uniprot.org/uniprot/TITIN_HUMAN TITIN_HUMAN] Key component in the assembly and function...
26: *[[Titin 3D structures|Titin 3D structures]] - 2nzi (7,720 bytes)
2: ==Crystal structure of domains A168-A170 from titin==
10: ...e TTN deletions, which lead to a total absence of titin's C-terminal end from striated muscles and to sec...
12: [https://www.uniprot.org/uniprot/TITIN_HUMAN TITIN_HUMAN] Key component in the assembly and function...
25: ...nition. Our findings indicate that this region of titin could serve as a target to attempt therapeutic in...
27: ...itment of the ubiquitin-ligase MuRF-1 onto M-line titin.,Mrosek M, Labeit D, Witt S, Heerklotz H, von Cas... - 8q4g (3,882 bytes)
13: ...un along the entire length of the thick filament, titin-beta chains do not. The structure also demonstrat... - Myotilin (814 bytes)
4: ...-terminal contails two Ig-like domains similar to titin<ref>PMID:10369880</ref>. See details in [[Group:... - 1bpv (7,790 bytes)
2: ==TITIN MODULE A71 FROM HUMAN CARDIAC MUSCLE, NMR, 50 STR...
10: ...e TTN deletions, which lead to a total absence of titin's C-terminal end from striated muscles and to sec...
12: [https://www.uniprot.org/uniprot/TITIN_HUMAN TITIN_HUMAN] Key component in the assembly and function...
25: ...n all of the interfaces between type I modules in titin. This conservation would lead to a regular multip...
27: ...ree-dimensional structure of a type I module from titin: a prototype of intracellular fibronectin type II... - 9rhk (229 bytes)
7: Description: Solution NMR structure of the titin I-band tandem I82-I83
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