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1. Image:Top2 770topzoomin.pdb (0 bytes)
2. Image:Top2 770top.pdb (0 bytes)
3. Image:Top2.png (0 bytes)
4. Image:Image- Top2.jpg (58 bytes)

Page text matches

1. 4gew (2,154 bytes)
   11: ...nd complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phos...
2. 4gz2 (3,142 bytes)
   11: ...osphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activi...
3. Sandbox Reserved 390 (7,877 bytes)
   3: ...iki/Podophyllotoxin podophyllotoxin] [[Image:PODO.png|thumb|right|50 px|Chemical structure of podophyll...
   10: ...diester bonds four base pairs apart, generating a TOP2-DNA cleavage complex.
   12: ...e> (all in green), exploit this harmful aspect of TOP2 and promote the formation of cytotoxic DNA lesion...
   14: ...his structure provided the first observation of a TOP2 ternary cleavage complex <scene name='Sandbox_Res...
   16: ..., it is desirable to develop the isoform specific TOP2-targeting agents.
4. 2rgr (4,240 bytes)
   11: [https://www.uniprot.org/uniprot/TOP2_YEAST TOP2_YEAST] Control of topological states of DNA by tr...
   24: ...f Saccharomyces cerevisiae Topo II (also known as Top2) and a gate-DNA segment. The structure reveals th...
5. 4gyz (3,271 bytes)
   11: ...osphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activi...
6. 4gz0 (5,345 bytes)
   12: ...osphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activi...
7. Ketosteroid Isomerase (23,709 bytes)
   14: [[Image:top2.png|thumb|left|450px|'''Topology diagram of KSI's str...
   23: [[Image: helix_capping_motifs.png|thumb|left|450px|'''Examples of C-terminal helix ...
   35: [[Image:beta-turn.png|thumb|right|250px|'''Type-II &beta;-turn between ...
   44: [[Image:dimer_interface.png|thumb|left|450px|'''Interactions at KSI's dimer i...
   46: [[Image:Kim1.png|thumb|right|175px|'''Water mediated dimer interac...
8. 4j3n (4,147 bytes)
   11: [https://www.uniprot.org/uniprot/TOP2B_HUMAN TOP2B_HUMAN] Control of topological states of DNA by t...
   14: ...to facilitate the development of isoform-specific Top2-targeting anticancer agents.
9. 4gz1 (5,311 bytes)
   12: ...osphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activi...
10. 3qx3 (3,907 bytes)
    11: [https://www.uniprot.org/uniprot/TOP2B_HUMAN TOP2B_HUMAN] Control of topological states of DNA by t...
    14: ...ion applicable for developing an isoform-specific TOP2-targeting strategy.
11. 4f1h (2,623 bytes)
    11: ...nd complexes between DNA and the topoisomerase 2 (top2) active site tyrosine residue. Hydrolyzes 5'-phos...
12. 4f1i (3,803 bytes)
    11: ...nd complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phos...
13. 4fpv (2,615 bytes)
    11: ...nd complexes between DNA and the topoisomerase 2 (top2) active site tyrosine residue. Hydrolyzes 5'-phos...
14. 4fva (2,284 bytes)
    11: ...nd complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phos...
15. 4g0u (4,262 bytes)
    11: [https://www.uniprot.org/uniprot/TOP2B_HUMAN TOP2B_HUMAN] Control of topological states of DNA by t...
    14: ...to facilitate the development of isoform-specific Top2-targeting anticancer agents.
16. 4g0v (4,289 bytes)
    11: [https://www.uniprot.org/uniprot/TOP2B_HUMAN TOP2B_HUMAN] Control of topological states of DNA by t...
    14: ...to facilitate the development of isoform-specific Top2-targeting anticancer agents.
17. 4g0w (4,274 bytes)
    11: [https://www.uniprot.org/uniprot/TOP2B_HUMAN TOP2B_HUMAN] Control of topological states of DNA by t...
    14: ...to facilitate the development of isoform-specific Top2-targeting anticancer agents.
18. 4puq (5,232 bytes)
    11: ...osphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activi...
    14: ...inkase). In this study, we show that irreversible Top2cc induced in suicidal substrates are not processe...
    16: ...Topoisomerase II (Top2) Enables the Processing of Top2-DNA and -RNA Covalent Complexes by Tyrosyl-DNA-ph...
19. 4put (1,904 bytes)
    2: ==Crystal structure of the Arabidopsis thaliana TOP2 oligopeptidase==
20. 5j3s (5,651 bytes)
    13: ...osphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activi...

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