We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

Edit this page

From Proteopedia

for User:Wayne Decatur/Sandbox Thermus 70S With Paromomycin

Jump to: navigation, search

You do not have permission to do that, for the following reasons:

The action you have requested is limited to users in the group user.
The database is currently locked to new entries and other modifications, probably for routine database maintenance, after which it will be back to normal. The administrator who locked it offered this explanation:
During hardware upgrade, Proteopedia remains in read-only mode.
Please try again in a few days for page editing/creation

You can view and copy the source of this page:

Ribosome interactions with Paromomycin



==Mechanism of action==
{|
|-valign="top"
| <applet load='Paromomycinfrom2j00.pdb.gz' size='390' frame='true' align='left' scene='User:Wayne_Decatur/Sandbox_Thermus_70S_With_Paromomycin/Paromomycin/1' />
||
|<table width='410' align='left' cellpadding='5'><tr><td rowspan='2'>&nbsp;</td><td bgcolor='#eeeeee'><applet load='2j01and2j00andrestofAsitetRNAalphac.pdb.gz' size='410' frame='true' align='right' scene='User:Wayne_Decatur/Sandbox_Thermus_70S_With_Paromomycin/70swithpar/1' /></td></tr><tr><td bgcolor='#eeeeee'><center>'''Paromomycin bound to the ribosome''' ([[2j01]] and [[2j00]), resolution 2.8&Aring; (<scene name='User:Wayne_Decatur/Sandbox_Thermus_70S_With_Paromomycin/70swithpar/1'>initial scene</scene>). <br>
·· {{Link Toggle halolsuriborRNAb}} ·· {{Link Toggle halolsu23SrRNAb}} ·· {{Link Toggle halolsu5SrRNAb}} ··<br>·· {{Link Toggle 70SriboProtein}} ·· {{Link Toggle BlackWhiteBackground}}  ··</center></td></tr></table>
|}

SSU alone with PAR


Ramakrishnan one with Par

<table width='550' align='right' cellpadding='5'><tr><td rowspan='2'>&nbsp;</td><td bgcolor='#eeeeee'><applet load='2j01and2j00andrestofAsitetRNAalphac.pdb.gz' size='540' frame='true' align='right' scene='User:Wayne_Decatur/Sandbox_Thermus_70S_With_Paromomycin/70swithpar/1' /></td></tr><tr><td bgcolor='#eeeeee'><center>'''Paromomycin bound to the ribosome''' ([[2j01]] and [[2j00]), resolution 2.8&Aring; (<scene name='User:Wayne_Decatur/Sandbox_Thermus_70S_With_Paromomycin/70swithpar/1'>initial scene</scene>). <br>
·· {{Link Toggle 70SribotRNAs}} ·· {{Link Toggle 70SribomRNA}} ·· {{Link Toggle 70SriborRNA}} ·· {{Link Toggle 70SriboProtein}} ··<br>
·· {{Link Toggle 70SriboAsitetRNA}} ·· {{Link Toggle 70SriboPsitetRNA}} ·· {{Link Toggle 70SriboEsitetRNA}} ·· <br>
·· {{Link Toggle 70SriboLSU}} ·· {{Link Toggle 70SriboSSU}} ·· {{Link Toggle BlackWhiteBackground}}  ·· <br></center></td></tr></table>

<scene name='User:Wayne_Decatur/Sandbox_Thermus_70S_With_Paromomycin/70swithpar/1'>TextToBeDisplayed</scene>

Add the e. coli 70S that has two molecules bound


<ref>PMID: 12765838</ref>
<ref>PMID: 12464183</ref>
<ref>PMID: 11340196</ref>
<ref>PMID: 11014183</ref>
<ref>PMID: 17660832</ref>
<ref>PMID: 17116475</ref>
<ref>PMID: 16569869</ref>
<ref>PMID: 12517339</ref>
<ref>PMID: 15491801</ref>

==References==
<references />

==Additional Literature and Resources==
<ref group="xtra">PMID:15491801</ref>
<references group="xtra"/> 
*[http://www.drugbank.ca/drugs/DB01421 Paramomycin at the DrugBank database]
*[http://en.wikipedia.org/wiki/Paromomycin_sulfate Paromomycin sulfate at Wikipedia]

Templates used on this page:

Return to Main Page.

Retrieved from "http://52.214.119.220/wiki/index.php/User:Wayne_Decatur/Sandbox_Thermus_70S_With_Paromomycin"

Edit this page

From Proteopedia

During hardware upgrade, Proteopedia remains in read-only mode.
Please try again in a few days for page editing/creation

Views

Personal tools

Navigation

Search

Toolbox

Edit this page

From Proteopedia

During hardware upgrade, Proteopedia remains in read-only mode. Please try again in a few days for page editing/creation

Views

Personal tools

Navigation

Search

Toolbox

During hardware upgrade, Proteopedia remains in read-only mode.
Please try again in a few days for page editing/creation