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Colicin E3 is a type of [[Colicin]], a bacteriocin made by ''E. Coli'' which acts against other nearby ''E. Coli'' to kill them with its 16s rRNase activity; it digests the 16s ribosomal subunit, ultimately leading to the death of the cell. ==Synthesis and release== ==Mechanism of uptake== {{STRUCTURE_1ujw | PDB=1ujw | SCENE= }} ColE3 initially binds to the BtuB vitamin B12 receptor. Formation of this complex leads to the unfolding of the N terminal receptor binding coiled-coil domain of ColE3. <ref> PMID: 17277071 </ref> The structure shows the complex formed between BtuB and the ColE3 translocation domain <ref> PMID: 14528295 </ref> ==Killing Activities== ==References== <references/>

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