3gi2
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | {{Seed}} | |
| + | [[Image:3gi2.jpg|left|200px]] | ||
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_3gi2", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| + | or leave the SCENE parameter empty for the default display. | ||
| + | --> | ||
| + | {{STRUCTURE_3gi2| PDB=3gi2 | SCENE= }} | ||
| - | + | ===Human dihydrofolate reductase Q35K mutant inhibitor complex=== | |
| - | Description: Human dihydrofolate reductase Q35K mutant inhibitor complex | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_19719239}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 19719239 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_19719239}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | 3GI2 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GI2 OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:19719239</ref><references group="xtra"/> | ||
| + | [[Category: Dihydrofolate reductase]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Cody, V.]] | ||
| + | [[Category: Active site mutant]] | ||
| + | [[Category: Dihydrofolate reductase]] | ||
| + | [[Category: Folate enzyme]] | ||
| + | [[Category: Nadp]] | ||
| + | [[Category: One-carbon metabolism]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 09:12:55 2009'' | ||
Revision as of 07:12, 30 September 2009
Human dihydrofolate reductase Q35K mutant inhibitor complex
Template:ABSTRACT PUBMED 19719239
About this Structure
3GI2 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Gangjee A, Li W, Kisliuk RL, Cody V, Pace J, Piraino J, Makin J. Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents. J Med Chem. 2009 Aug 13;52(15):4892-902. PMID:19719239 doi:10.1021/jm900490a
Page seeded by OCA on Wed Sep 30 09:12:55 2009
