3imc

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(New page: '''Unreleased structure''' The entry 3imc is ON HOLD until Paper Publication Authors: Ciulli, A., Hung, A.W., Silvestre, H.L., Wen, S., Blundell, T.L., Abell, C. Description: Crystal S...)
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'''Unreleased structure'''
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[[Image:3imc.jpg|left|200px]]
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The entry 3imc is ON HOLD until Paper Publication
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{{STRUCTURE_3imc| PDB=3imc | SCENE= }}
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Authors: Ciulli, A., Hung, A.W., Silvestre, H.L., Wen, S., Blundell, T.L., Abell, C.
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===Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.6 Ang resolution in complex with fragment compound 5-methoxyindole, sulfate and glycerol===
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Description: Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.6 Ang resolution in complex with fragment compound 5-methoxyindole, sulfate and glycerol
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 19 12:37:31 2009''
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==About this Structure==
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3IMC is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMC OCA].
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==Reference==
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<ref group="xtra">PMID:19780086</ref><references group="xtra"/>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Pantoate--beta-alanine ligase]]
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[[Category: Abell, C.]]
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[[Category: Blundell, T L.]]
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[[Category: Ciulli, A.]]
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[[Category: Hung, A W.]]
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[[Category: Silvestre, H L.]]
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[[Category: Wen, S.]]
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[[Category: Atp-binding]]
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[[Category: Cytoplasm]]
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[[Category: Drug design]]
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[[Category: Enzyme]]
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[[Category: Fragment-based]]
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[[Category: Ligase]]
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[[Category: Magnesium]]
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[[Category: Metal-binding]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Nucleotide-binding]]
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[[Category: Pantothenate biosynthesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 14 10:25:31 2009''

Revision as of 08:25, 14 October 2009

Image:3imc.jpg

Template:STRUCTURE 3imc

Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.6 Ang resolution in complex with fragment compound 5-methoxyindole, sulfate and glycerol

About this Structure

3IMC is a 2 chains structure of sequences from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Hung AW, Silvestre HL, Wen S, Ciulli A, Blundell TL, Abell C. Application of fragment growing and fragment linking to the discovery of inhibitors of Mycobacterium tuberculosis pantothenate synthetase. Angew Chem Int Ed Engl. 2009;48(45):8452-6. PMID:19780086 doi:10.1002/anie.200903821

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