2bgo
From Proteopedia
(New page: 200px<br /> <applet load="2bgo" size="450" color="white" frame="true" align="right" spinBox="true" caption="2bgo" /> '''MANNAN BINDING MODULE FROM MAN5C'''<br /> ...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2BGO is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BGO OCA]]. | + | 2BGO is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]]. Structure known Active Site: M. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BGO OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: mannan]] | [[Category: mannan]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:45:45 2007'' |
Revision as of 06:41, 30 October 2007
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MANNAN BINDING MODULE FROM MAN5C
Overview
Enzymes that digest plant cell wall polysaccharides generally contain, non-catalytic, carbohydrate-binding modules (CBMs) that function by, attaching the enzyme to the substrate, potentiating catalytic activity., Here, we present the first structure of a family 35 CBM, derived from the, Cellvibrio japonicus beta-1,4-mannanase Man5C. The NMR structure has been, determined for both the free protein and the protein bound to, mannopentaose. The data show that the protein displays a typical, beta-jelly-roll fold. Ligand binding is not located on the concave surface, of the protein, as occurs in many CBMs that display the jelly-roll fold, but is formed by the loops that link the two beta-sheets of the protein, similar to family 6 CBMs. In contrast to the majority of CBMs, which are, generally ... [(full description)]
About this Structure
2BGO is a [Single protein] structure of sequence from [Cellvibrio japonicus]. Structure known Active Site: M. Full crystallographic information is available from [OCA].
Reference
Structure of a mannan-specific family 35 carbohydrate-binding module: evidence for significant conformational changes upon ligand binding., Tunnicliffe RB, Bolam DN, Pell G, Gilbert HJ, Williamson MP, J Mol Biol. 2005 Mar 25;347(2):287-96. PMID:15740741
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