This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1a65
From Proteopedia
(New page: 200px<br /> <applet load="1a65" size="450" color="white" frame="true" align="right" spinBox="true" caption="1a65, resolution 2.23Å" /> '''TYPE-2 CU-DEPLETED ...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1A65 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Coprinus_cinereus Coprinus cinereus]] with NAG, GLC, CU and O as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1A65 OCA]]. | + | 1A65 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Coprinus_cinereus Coprinus cinereus]] with NAG, GLC, CU and O as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2]]. Structure known Active Sites: T1 and T3. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1A65 OCA]]. |
==Reference== | ==Reference== | ||
| Line 27: | Line 27: | ||
[[Category: type-2 copper depleted]] | [[Category: type-2 copper depleted]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:48:21 2007'' |
Revision as of 06:43, 30 October 2007
|
TYPE-2 CU-DEPLETED LACCASE FROM COPRINUS CINEREUS
Overview
Laccase catalyses the oxidation of a variety of organic substrates coupled, to the reduction of oxygen to water. It is widely believed to be the, simplest representative of the ubiquitous blue multi-copper oxidase, family. Laccase is implicated in a wide spectrum of biological activities, and, in particular, plays a key role in morphogenesis, development and, lignin metabolism in fungi and plants. The structure of laccase from the, fungus Coprinus cinereus has been determined by X-ray crystallography at a, resolution of 2.2 A. Laccase is a monomer composed of three, cupredoxin-like beta-sandwich domains, similar to that found in ascorbate, oxidase. In contrast to ascorbate oxidase, however, the mononuclear type-1, Cu site lacks the axial methionine ligand and so exhibits trigonal planar, ... [(full description)]
About this Structure
1A65 is a [Single protein] structure of sequence from [Coprinus cinereus] with NAG, GLC, CU and O as [ligands]. Active as [Oxidoreductase], with EC number [1.10.3.2]. Structure known Active Sites: T1 and T3. Full crystallographic information is available from [OCA].
Reference
Crystal structure of the type-2 Cu depleted laccase from Coprinus cinereus at 2.2 A resolution., Ducros V, Brzozowski AM, Wilson KS, Brown SH, Ostergaard P, Schneider P, Yaver DS, Pedersen AH, Davies GJ, Nat Struct Biol. 1998 Apr;5(4):310-6. PMID:9546223
Page seeded by OCA on Tue Oct 30 08:48:21 2007
Categories: Coprinus cinereus | Single protein | Brzozowski, W. | Ducros, V. | CU | GLC | NAG | O | Blue multi-copper oxidase | Glycoprotein | Laccase | Oxidoreductase | Signal | Type-2 copper depleted
