1a52

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==About this Structure==
==About this Structure==
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1A52 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The September 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Estrogen Receptor'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_9 10.2210/rcsb_pdb/mom_2003_9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A52 OCA].
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1A52 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The September 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Estrogen Receptor'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_9 10.2210/rcsb_pdb/mom_2003_9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A52 OCA].
==Reference==
==Reference==
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[[Category: Estrogen Receptor]]
[[Category: Estrogen Receptor]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: RCSB PDB Molecule of the Month]]
[[Category: Sigler, P B.]]
[[Category: Sigler, P B.]]
[[Category: Tanenbaum, D M.]]
[[Category: Tanenbaum, D M.]]
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[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:47:51 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 08:10:46 2010''

Revision as of 06:10, 21 January 2010

Template:STRUCTURE 1a52

Contents

ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN COMPLEXED TO ESTRADIOL

Template:ABSTRACT PUBMED 9600906

Disease

Known disease associated with this structure: Breast cancer OMIM:[133430], Estrogen resistance OMIM:[133430], Atherosclerosis, susceptibility to OMIM:[133430], HDL response to hormone replacement, augmented OMIM:[133430], Migraine, susceptibility to OMIM:[133430], Myocardial infarction, susceptibility to OMIM:[133430]

About this Structure

1A52 is a 2 chains structure with sequences from Homo sapiens. The September 2003 RCSB PDB Molecule of the Month feature on Estrogen Receptor by David S. Goodsell is 10.2210/rcsb_pdb/mom_2003_9. Full crystallographic information is available from OCA.

Reference

  • Tanenbaum DM, Wang Y, Williams SP, Sigler PB. Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains. Proc Natl Acad Sci U S A. 1998 May 26;95(11):5998-6003. PMID:9600906

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