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Template:STRUCTURE 1hsg

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Revision as of 06:33, 21 January 2010

1hsg, resolution 2.00Å ()

Sites:

Ligands:

Gene:

HIV-1 PROTEASE FROM THE NY5 ISOLATE (Human immunodeficiency virus 1)

Structural annotation:
Resources:	CATH : 1Hsga00, 1Hsgb00 InterPro : Ipr010659, Ipr010999, Ipr001995, Ipr008916, Ipr010661, Ipr002156, Ipr001878, Ipr000071, Ipr000721, Ipr012337, Ipr001037, Ipr009007, Ipr001969, Ipr008919, Ipr003308, Ipr000477, Ipr013084, Ipr001584 Pfam : PF00077 SCOP : d1hsga_, d1hsgb_ UniProt : P03367

Functional annotation:
Cellular component:	cytoplasm viral nucleocapsid nucleus membrane viral capsid virion
Biological process:	viral reproduction viral procapsid maturation DNA integration proteolysis DNA recombination RNA-dependent DNA replication transposition, DNA-mediated
Molecular function:	hydrolase activity nucleotidyltransferase activity ribonuclease H activity nucleic acid binding aspartic-type endopeptidase activity peptidase activity endonuclease activity DNA binding transferase activity RNA-directed DNA polymerase activity metal ion binding structural molecule activity RNA binding magnesium ion binding DNA-directed DNA polymerase activity zinc ion binding nuclease activity catalytic activity integrase activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_1hsg"

@@ Line 1: / Line 1: @@
 {{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1hsg]], resolution 2.00&Aring; (<scene name='initialview01'>default scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1hsg]], [[Resolution|resolution]] 2.00&Aring; (<scene name='initialview01'>default scene</scene>)}}}
+|SITE= <scene name='pdbsite=AC1:Binding+Site+For+Residue+Mk1+B+902'>AC1</scene>
 |LIGAND= <scene name='pdbligand=MK1:N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY+BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE'>MK1</scene>
 |GENE= HIV-1 PROTEASE FROM THE NY5 ISOLATE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00077 RVP]</span>
 |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hsg OCA], [http://www.ebi.ac.uk/pdbsum/1hsg PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hsg RCSB]</span>
 |FUNCTION={{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0016779 | text = nucleotidyltransferase activity}}{{GO|id=GO:0004523 | text = ribonuclease H activity}}{{GO|id=GO:0003676 | text = nucleic acid binding}}{{GO|id=GO:0004190 | text = aspartic-type endopeptidase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0004519 | text = endonuclease activity}}{{GO|id=GO:0003677 | text = DNA binding}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0003964 | text = RNA-directed DNA polymerase activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0005198 | text = structural molecule activity}}{{GO|id=GO:0003723 | text = RNA binding}}{{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0003887 | text = DNA-directed DNA polymerase activity}}{{GO|id=GO:0008270 | text = zinc ion binding}}{{GO|id=GO:0004518 | text = nuclease activity}}{{GO|id=GO:0003824 | text = catalytic activity}}{{GO|id=GO:0008907 | text = integrase activity}}
@@ Line 9: / Line 9: @@
 |COMPONENT={{GO|id=GO:0005737 | text = cytoplasm}}{{GO|id=GO:0019013 | text = viral nucleocapsid}}{{GO|id=GO:0005634 | text = nucleus}}{{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0019028 | text = viral capsid}}{{GO|id=GO:0019012 | text = virion}}
 |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hsgA00 1Hsga00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hsgB00 1Hsgb00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010659 Ipr010659], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010999 Ipr010999], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001995 Ipr001995], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008916 Ipr008916], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010661 Ipr010661], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002156 Ipr002156], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001878 Ipr001878], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000071 Ipr000071], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000721 Ipr000721], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR012337 Ipr012337], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001037 Ipr001037], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR009007 Ipr009007], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001969 Ipr001969], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008919 Ipr008919], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR003308 Ipr003308], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000477 Ipr000477], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013084 Ipr013084], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001584 Ipr001584]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00077 PF00077]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=26541 d1hsga_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=26542 d1hsgb_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P03367 P03367]</span>
-|CONSURF={{!}}-
+|uPDB=1HSG|CONSURF={{!}}-
 {{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
 {{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"

Template:STRUCTURE 1hsg

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Revision as of 06:33, 21 January 2010

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