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2x0u

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(New page: '''Unreleased structure''' The entry 2x0u is ON HOLD Authors: Joerger, A.C., Kaar, J.L., Basse, N., Fersht, A.R. Description: STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO A 2...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:2x0u.jpg|left|200px]]
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The entry 2x0u is ON HOLD
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{{STRUCTURE_2x0u| PDB=2x0u | SCENE= }}
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Authors: Joerger, A.C., Kaar, J.L., Basse, N., Fersht, A.R.
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===STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO A 2-AMINO SUBSTITUTED BENZOTHIAZOLE SCAFFOLD===
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Description: STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO A 2-amino substituted benzothiazole scaffold
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 23 09:13:02 2009''
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==About this Structure==
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2X0U is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X0U OCA].
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==Reference==
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<ref group="xtra">PMID:17015838</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Basse, N.]]
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[[Category: Fersht, A R.]]
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[[Category: Joerger, A C.]]
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[[Category: Kaar, J L.]]
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[[Category: Activator]]
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[[Category: Apoptosis]]
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[[Category: Cancer]]
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[[Category: Cell cycle]]
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[[Category: Host-virus interaction]]
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[[Category: Li-fraumeni drug discovery]]
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[[Category: Metal binding]]
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[[Category: Protein stabilization]]
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[[Category: Surface crevice]]
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[[Category: Transcription]]
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[[Category: Transcription factor]]
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[[Category: Transcription regulation]]
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[[Category: Tumor suppressor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:55:31 2010''

Revision as of 17:55, 27 January 2010

Image:2x0u.jpg

Template:STRUCTURE 2x0u

STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO A 2-AMINO SUBSTITUTED BENZOTHIAZOLE SCAFFOLD

About this Structure

2X0U is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838

Page seeded by OCA on Wed Jan 27 19:55:31 2010

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