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2bfz
From Proteopedia
(Difference between revisions)
| Line 20: | Line 20: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2BFZ is a 2 chains structure | + | 2BFZ is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BFZ OCA]. |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:15779910</ref><references group="xtra"/> | + | <ref group="xtra">PMID:15779910</ref><ref group="xtra">PMID:11827530</ref><ref group="xtra">PMID:9730812</ref><references group="xtra"/> |
[[Category: Bacillus cereus]] | [[Category: Bacillus cereus]] | ||
[[Category: Beta-lactamase]] | [[Category: Beta-lactamase]] | ||
| Line 33: | Line 33: | ||
[[Category: Antibiotic resistance]] | [[Category: Antibiotic resistance]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| - | [[Category: Metallo-beta-lactamase]] | ||
| - | [[Category: Zinc]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 3 09:04:10 2010'' |
Revision as of 07:04, 3 February 2010
BACILLUS CEREUS METALLO-BETA-LACTAMASE (BCII) ARG (121) CYS MUTANT. SOLVED AT PH4.5 USING 20MM ZNSO4 IN BUFFER. 1MM DTT WAS USED AS A REDUCING AGENT. CYS221 IS OXIDIZED.
Template:ABSTRACT PUBMED 15779910
About this Structure
2BFZ is a 2 chains structure with sequences from Bacillus cereus. Full crystallographic information is available from OCA.
Reference
- Davies AM, Rasia RM, Vila AJ, Sutton BJ, Fabiane SM. Effect of pH on the active site of an Arg121Cys mutant of the metallo-beta-lactamase from Bacillus cereus: implications for the enzyme mechanism. Biochemistry. 2005 Mar 29;44(12):4841-9. PMID:15779910 doi:10.1021/bi047709t
- Rasia RM, Vila AJ. Exploring the role and the binding affinity of a second zinc equivalent in B. cereus metallo-beta-lactamase. Biochemistry. 2002 Feb 12;41(6):1853-60. PMID:11827530
- Fabiane SM, Sohi MK, Wan T, Payne DJ, Bateson JH, Mitchell T, Sutton BJ. Crystal structure of the zinc-dependent beta-lactamase from Bacillus cereus at 1.9 A resolution: binuclear active site with features of a mononuclear enzyme. Biochemistry. 1998 Sep 8;37(36):12404-11. PMID:9730812 doi:http://dx.doi.org/10.1021/bi980506i
Page seeded by OCA on Wed Feb 3 09:04:10 2010
