Collagen Structure & Function
From Proteopedia
(Difference between revisions)
(→Molecular Structure) |
|||
| Line 6: | Line 6: | ||
==Molecular Structure== | ==Molecular Structure== | ||
| - | Collagen takes the form of a triple helix. | + | Collagen takes the form of a triple helix which is stabilized by hydrogen bonding. |
| + | Each helix is enclosed by a hydration cylinder. | ||
==Collagen-Related Disorders== | ==Collagen-Related Disorders== | ||
Revision as of 01:37, 22 March 2010
Contents |
Collagen
Introduction
Collagen is a member of a naturally occurring protein family. In nature is is found in animals and is responsible for a variety of biological functions.
Molecular Structure
Collagen takes the form of a triple helix which is stabilized by hydrogen bonding. Each helix is enclosed by a hydration cylinder.
Collagen-Related Disorders
There are currently close to 30 different types of collagen that have been identified. The most abundant type of collagen present in the human body is that of Type I.
- Type I- found in bones,tendons,organs
- Type II-found mainly in cartilage
- Type III-found mainly in reticular fibres
- Type IV-present in the basement membrane of cell membranes
- Type V-common in hair
| |||||||
| 1cag, resolution 1.85Å () | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Non-Standard Residues: | |||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Proteopedia Page Contributors and Editors (what is this?)
Daman K. Kandola, Alexander Berchansky, David Canner, Andrea Gorrell, Luis Netto
